| I definitely agree with Iain's comment - I don't think that people will change their practice on the basis of one study. without seeing the original it's difficult to comment, but my first thoughts were
1. What tissues do in a dish is not necessarily what they do in a person
2. tests on healthy child volunteers to not necessarily translate to the same results on sick adults
(Obviously both the above methods are used in testing new treatments anyway and so i am not dismissing them - merely saying that one should be cautious with interpretation of the results)
3. unless you have intubated the patient you will not be giving them 100% oxygen. Even a tight fitting face mask with high flow O2 is likely to be giving around 85-90% so you will be getting some CO2 in there.
4. Would you be happy to be a guinea pig for the "wait and see" approach? the only way to tell if this is better is to randomise your resus patients into high/ low FiO2 and I know which arm I'd want to be in!
Will be sticking with as much O2 as i can stuff in my patients for now!  |