To be honest John I think the discussion is pretty much the same as to invert or not period.
It may make shut down easier, but may complicate after failiure procedures such as a team member assisting with diagnostics and signalling to each other. It also means that the rest of your team has to be familiar with an inverted set up and subsequent hose routing/valve postioning. This may be difficult if they do not dive an inverted set up themselves
One thing that was hammered into us was elimination of secondary problems and inverting tanks for a cave course just looks like creating more issues than its solving. You can do a cave course on single tank and really enjoy it
